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In response to the above questions: The type of exception you have is normally thrown by a method that’s running in code (usually Java, C#, C++, etc) that’s running on a remote machine, in which case you need to call a different method that’s running in the Java VM that’s running on your local machine. Akt1 contributes to the oncogenic and tumor promotional activities of polyoma middle T antigen. The B-lymphocytic cell line, XG-2, which is derived from a spontaneously arising mouse lymphoma, harbors polyoma middle T antigen (PyMT), a potent oncogenic and tumor promotional protein, in its genome. In this study, by using a cDNA microarray analysis, we have identified a novel PyMT-responsive gene, Akt1, which belongs to the Akt family of serine-threonine protein kinases. The activation of Akt1 by PyMT was confirmed by Western blotting and immunoprecipitation analyses. The involvement of Akt1 in PyMT-induced tumor promotion was shown by the findings that overexpression of the wild-type Akt1 gene enhanced both cellular transformation and the tumor-promoting activity of PyMT. Conversely, a dominant-negative Akt1 mutant (K179M) inhibited the tumor-promoting activity of PyMT. These results indicate that Akt1 is involved in the tumor-promoting activity of PyMT. Consistent with this, Akt1 was found to be activated in some human breast cancers and to be translocated to the nucleus. These results suggest that Akt1 contributes to the PyMT-induced transformation and tumor promotion in XG-2 cells by a novel mechanism that is unrelated to its well-known role in phosphatidylinositol 3-kinase signaling.1941 All-Pro Team The following was composed of the best players at each position, as determined by a poll of “New York Daily News” sportswriters and sports editors. The team was announced on January 5, 1941. Teams References Category:All-Pro Teams Category:1940s in American football Category:Pro Football Hall of Fame Championship seasons Category:Sports in Pittsburgh Category:Pro Football Hall of Fame Game TEXAS COURT OF APPEALS, THIRD DISTRICT, AT AUSTIN NO. 03-11-00 6d1f23a050


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